RNA Details
Disease Name
diabetic nephropathy
Tissue
kidney
RNA Symbol
Oip5os1
RNA ID
RNA Type
lncrna
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
dual-luciferase reporter assay
Target
NA
Pathway
HIF-1 SIGNALING PATHWAY
PubMed ID
Title
LincRNA 1700020I14Rik alleviates cell proliferation and fibrosis in diabetic nephropathy via miR-34a-5p/Sirt1/HIF-1alpha signaling
Year
2018
Function
Overexpression of 1700020i14rik inhibited cell proliferation and expressions of renal fibrosis markers through miR-34a-5p/sirt1/hif-1 alfa pathway in mouse mesangial cells under high glucose condition.